Sunday, April 14, 2019

Circadian Rhythms, Biological Clock and Health

A circadian (24-hour) rhythms are driven by a circadian clock, and they have been widely observed in plants, animals, fungi, and cyanobacteria.

Biological clock humanThere is strong data to suggest CR disturbances, due to either shift work, sleep disorders or frequent travel between time zones, has negative impact on health. 
Circadian Rhythms: Will It Revolutionise the Management of Diseases? (

Currently, in developed countries, nights are excessively illuminated (light at night), whereas daytime is mainly spent indoors, and thus people are exposed to much lower light intensities than under natural conditions. In spite of the positive impact of artificial light, we pay a price for the easy access to light during the night: disorganization of our circadian system or chronodisruption (CD), including perturbations in melatonin rhythm. Epidemiological studies show that CD is associated with an increased incidence of diabetes, obesity, heart disease, cognitive and affective impairment, premature aging and some types of cancer.  Protecting the Melatonin Rhythm through Circadian Healthy Light Exposure (
NIGMS, the National Institutes of Health resources on Circadian Rhythms and sleep: 

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