Saturday, July 4, 2020

Gridcoin to reward volunteers to compute for science with BOINC

Gridcoin rewards computations with BOINC and compensated part of electricity cost.

BOINC client can be installed on a PC or Android phone to participate in a research of scientific projects in life science, physic, math and other fields.

Grcpool has to be used to select projects and connect to BOINC client to manage project progress and compute gridcoin rewards.

Gridcoin.us is an internet page of the Grindcoin project and Price of the coin can be found as follows:


https://www.coingecko.com/en/coins/gridcoin-research

Although Gridcoin does not compensate electricity cost of computing, this is still rewarding and add some positivity in scientific contributions by volunteers.

Sunday, June 14, 2020

Donate mobile phone or a PC power to the scientific research

World Community Grid perform scientific research by sending computational tasks to a distributed network of private devices.

BOINC installation is required and Android app can be easily installed via Google play.

BOINC app is very handy and has a lot of customisation in relation to the usage. It can be set up to be used only when screen is inactive, or phone is charging, or at a specific battery level. If is a please to use BOINC app.

Other research projects can be added.

It may be practical to use second mobile or even an old device - mobile or a tablet, for a test. Most economical, however, is to use a regular devise which is anyway switched on and working to get use of it's iddle time.

If you like to join me in this research  journey, please register with a referral link below.


 

Saturday, May 9, 2020

Folding@home with unused laptop resources for science

Protein Folding, or how to predict the 3D structure of proteins from 1D sequence, is a key task in molecular biology which is not yet resolved.

Folding@home is an oldest citizen science project i know. The project has started in October 2000 and now approaches its 20th anniversary.

Anyone can fold at home with a personal computer. The Folding@home software will run in the background, eat some free resources and fold the proteins for several projects including Oncology and COVID-19.

It does not slow down my laptop as i writing this post running The Folding@home in the background.

Software installation is here: https://foldingathome.org/start-folding/
Scientific part & publications of results: https://foldingathome.org/category/science/
Competing (donating resources) teams: https://stats.foldingathome.org/teams

Sunday, March 8, 2020

How to learn about Blockchain?-> try it!

Photomania.net
The best way to learn about Blockchain is to try it.


Option with NANO:
1. Get free NANO wallet, f.e. https//natrium.io/

2. try NANO faucets to get some free NANO


Option to try with Ethereum and get free ERC-20 tokens:
  1. Create free Ether wallet on Ether website or with Ether app . Make sure to back up passwords and keys.
  2. Earn some tokens with Publish0x or Brave browser (if you have a website) .
  3. Transfer tokens to Ether or other wallet.

More free ERC-20 tokens with:
Uptrennd - 20 1up tokens daily for reading.  Earn by writing posts and commenting. Welcome bonus with referral link: https://www.uptrennd.com/signup/Njg2MzA


Bitcoin or DOGE with watching adds:
CoinTiply - hight payout threshold, may require some time if watching adds only. There are options to advertise.
DOGE Telegram tip bot. Boring but there is option to advertise. Payout is 4 DOGE and good to test a wallet.

Other coins:
Getzen faucet- Horizen blockchain. Daily free coins to Horizen wallet
Bitcoin cash - weekly payout, low threshold. Perfect to test a wallet.
Free litcoin - weekly payout, low threshold. Perfect to test a wallet.
LBRY - LBC coins to watch and post video or text content.
Tezos faucet - once a week to test Tezos blockchain
BCH tipbot - boring but option to advertise

Free coins on exchanges: 
Atomars - DOGE, BAN, TRX and other coins free.
Atomic wallet - 10AWC welcome bonus plus 5AWC for joining with referral (17K1PD). 10 USD amount in coins is required for this airdrop. Do not forget to stake AWC for passive income.
Graviex exchange - some free coins incl. DOGE

This post is not a financial or investment advice. 

Wednesday, February 26, 2020

Direct-to-Consumer Genetic Testing: Pros and Cons


Millions of people worldwide have taken the at-home genetic test (1,2). Ancestry tests are very popular, plus there is a growing offering of health-related tests.


There is still a fair amount of uncertainty about test results and the use of personal data. In table below, there is an attempt to summarize arguments in favor or against private testing.  (This is not a recommendation in favor of taking a test). 


Pros
Cons
Useful information (Ancestry, Relatives, Health).
Privacy. Others can use your information in the way you do not know or do not want.
Some tests can be done anonymously (without providing personal details).
Privacy. Anonymous tests sound impossible. 
Help Scientific research / Benefit from scientific results
Privacy. Possible discrimination (5), possible psychological Implications 
Financial incentive for sharing data
Privacy. Not clear regulation / GDPR 
Intriguing part of the decision making around taking or not taking DTC tests is that individuals can be still identified by DNA, even if not taking DNA tests. Either genetic databases or DNA markers can be used to learn about anonymous DNA and locate an individual.
Literature:
1. More than 270 Direct-to-Consumer Genetic Testing services are examined, their business models are classified in January 2020 publication of .'Valuable Genomes: Taxonomy and Archetypes of Business Models in Direct-to-Consumer Genetic Testing'. Comprehensive list of 448 DTC genetic companies is available @ publication sitehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001042/bin/jmir_v22i1e14890_app1.xlsx
2. More than 26 million people have taken an at-home ancestry test. The genetic genie is out of the bottle. And it’s not going back. https://www.technologyreview.com/s/612880/more-than-26-million-people-have-taken-an-at-home-ancestry-test/
3.Opportunities and challenges of Distributed Ledger Technology in genomics: a call for Europe are summarized in the article of . Opportunities are : flexibility and access advantaged to data exchange for research, Increased security, further democratization of data. Challenges are: size of genomic data set, uncertain regulatory especially GDPR, awareness of public towards genetic data.
4. A Ledger of Me: Personalizing Healthcare Using Blockchain Technology  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668357/
5. What is genetic discrimination? https://ghr.nlm.nih.gov/primer/testing/discrimination
6. A Systematic Review of the Psychological Implications of Genetic Testing: A Comparative Analysis Among Cardiovascular, Neurodegenerative and Cancer Diseases https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295518/
8. What is anonymous sequencing? https://nebula.org/anonymous-sequencing/
9. Facial recognition from DNA using face-to-DNA classifiers https://www.nature.com/articles/s41467-019-10617-y
10. Identification of Anonymous DNA Using Genealogical Triangulation https://www.biorxiv.org/content/10.1101/531269v1


12. The law of genetic privacy: applications, implications, and limitations
https://academic.oup.com/jlb/article/6/1/1/5489401

Sunday, January 26, 2020

Dog Aging Project -> Nominate your dog

The Dog Aging Project is a long-term biological study of aging in dogs, centered at the University of Washington.


The project engages the general public to register their dogs in the studies, and therefore the project is an example of citizen science..... A small subset of those dogs (approximately 500) will be enrolled in a double-blind, placebo-controlled study of the pharmaceutical rapamycin, which has shown signs of extending longevity in species such as mice.


Life Span <-> Health Span

Wednesday, December 25, 2019

Free Promethease reports & SNPedia

SNPedia is a wiki-based bioinformatics web site, a database of single nucleotide polymorphisms (SNPs).

Promethease is to compare personal genetics results from Myheritage, 23andme, Ancestry, FamilyTreeDNA, others gainst the SNPedia database.

Sample reports are available @ https://promethease.com/

Be sure to read privacy and data protection policy on websites of the companies, more on regulations of testings:

Friday, December 20, 2019

Crypto Social


Brave is a free and open-source web browser ...blocks ads and website trackers. The company has proposed adopting a pay-to-surf business model in a future version of the browser.

Brave allows users to support the sites they visit with BAT.[11] Users may earn BAT by watching ads or by funding their BAT wallet. Users are paid 70% of the revenue they generate. The remaining 30% is split between Brave and the advertisement's publisher.[12]

BAT token is traded on crypto exchanges and several major websites are registered as Brave publishers. Once Brave Browser (here with swca.ch referral) is installed, one can earn some BAT and share it with publishers. 
Coil.com enables users to pay websites and creators directly.
Swissborg community (Predict, learn and earn Bitcoin with zero risk) with it's own CHSB coin.  SWCA referral code: 4JNW5RA

Steemit (steemit.com) is a blockchain-based blogging and social media website, which rewards its users with the cryptocurrency STEEM for publishing and curating content, and is owned by Steemit Inc., a privately held company based in New York City and a headquarters in Virginia.



Sunday, November 10, 2019

Amanita muscaria

The toxins in Amanita muscaria are water-soluble ... the consumption of detoxified A. muscaria has been practiced in some parts of Europe (notably by Russian settlers in Siberia) since at least the 19th century, and likely earlier. 






This observation may imply that A. fulva under typical geochemical site conditions is able to regulate the accumulation of many of the elements mentioned in fruiting bodies :  Ag, Al, As, Ba, Ca, Cd, Co, Cu, Cr, Fe, K, Mg, Mn, Na, Ni, P, Pb, Rb, Sr, Tl, V, U and Zn



.... accumulation of U, Th, Pb and Ag in macrofungal fruit-bodies apparently does not depend on total content and chemical

fractionation of these metals in soils (tested by the BCR sequential extraction in this study).



Friday, October 4, 2019

Anonymous Sequencing & Oral Microbiome

Nebula Genomics offers anonymous sequencing with oral microbiome analysis, storing data on blockchain-based storage but yet in US only. (https://nebula.org/anonymous-sequencing)
Dante Labs performs tests in Italy and recently announced 10'000 Oral Microbiome project to improve oral care.

More on Oral Microbiome:



Wednesday, September 25, 2019

Whole Genome Sequencing for ... USD 600 = Unbelievable!

https://neural-labs.com/en/arti/Whole genome sequencing (WGS) is ostensibly the process of determining the complete DNA sequence of an organism's genome at a single time. 

The "$1,000 genome" phrase neatly highlighted the chasm between the actual cost of the Human Genome Project, estimated at $2.7 billion over a decade, and the benchmark for routine, affordable personal genome sequencing.

In 2010, Illumina introduced its individual genome sequencing service for consumers, who were required to present a doctor's note. The initial price was $50,000/person. One of the first clients was former Solexa CEO John West, who had his entire family of four sequenced.[22]
Now "$1,000 genome" is in past as there are number of companies offering WGS starting from USD 600.... 
Additional reading:
WGS should not be confused with Exome sequencing (WES) - a genomic technique for sequencing all of the protein-coding region of genes in a genome (known as the exome). 


Friday, September 20, 2019

Fighting Plastic waste with ...Kefir?

Home production of kefir requires kefir grains, Milk and 5 minutes time daily. Home production of Kefir may reduce consumption of packaged product and does not require plastic.

Where to get kefir grains? from friends making kefir already or from on-line shop
How to produce kefir @home?
Some Scientific articles on kefir research: 
and about plastic waste:




Some Room for -> Mushroom

Mushrooms as a source of Vitamin D:





Articles on Mushrooms vs. Immune System and/or Cancer:



Mushrooms in Clinical Trials:






More on Mushrooms:



Sunday, June 30, 2019

Favorite Photo Pages and Photo Commerce Sites


Get your photos exhibited in galleries around the world: Gurushots Exibitions.

Etsy: Millions of shoppers can’t wait to see what you have in store. My favorite store on Etsy: KindStoryArt.

Photomyne:  scan dozens of photos in minutes

Snapseed from Google: on-line and Android/iPhone apps

AI Editors: https://www.swca.ch/2019/03/best-photo-editing-applications.html

Friday, June 21, 2019

MOOD: to track or not to track?

Mood tracking is a positive psychology technique for improving mental health where a person records their mood, usually at set time intervals, in order to help identify patterns in how their mood varies.



Sunday, April 14, 2019

Circadian Rhythms, Biological Clock and Health



A circadian (24-hour) rhythms are driven by a circadian clock, and they have been widely observed in plants, animals, fungi, and cyanobacteria.

Biological clock humanThere is strong data to suggest CR disturbances, due to either shift work, sleep disorders or frequent travel between time zones, has negative impact on health. 
Circadian Rhythms: Will It Revolutionise the Management of Diseases? (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425903/)


Currently, in developed countries, nights are excessively illuminated (light at night), whereas daytime is mainly spent indoors, and thus people are exposed to much lower light intensities than under natural conditions. In spite of the positive impact of artificial light, we pay a price for the easy access to light during the night: disorganization of our circadian system or chronodisruption (CD), including perturbations in melatonin rhythm. Epidemiological studies show that CD is associated with an increased incidence of diabetes, obesity, heart disease, cognitive and affective impairment, premature aging and some types of cancer.  Protecting the Melatonin Rhythm through Circadian Healthy Light Exposure (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284776/)
NIGMS, the National Institutes of Health resources on Circadian Rhythms and sleep: https://www.nigms.nih.gov/education/pages/factsheet_circadianrhythms.aspx